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5月18日下午,2026国际基础科学大会(ICBS 2026)新闻发布会在清华大学举行,正式公布2026年基础科学奖章(ICBS Medal)及前沿科学奖(Frontiers of Science Award)获奖名单。9位中外顶尖科学家荣膺基础科学奖章,其中,克莱尔·瓦赞(Claire Voisin)、姚鸿泽(Horng-Tzer Yau)、张寿武荣膺数学领域基础科学奖章;刘若微(Andrea J. Liu)、王贻芳、文小刚荣膺物理领域基础科学奖章;鲍哲南、庄小威、张锋荣膺工程领域基础科学奖章。

作为2026年首次设立的重要奖项,基础科学奖章旨在表彰全球范围内在基础科学领域取得革命性、突破性成果的科学家,致敬他们对科学进步作出的卓越贡献。奖章正面为科学巨匠头像,背面镌刻“钩玄穷理,搜美求真”(For Truth and Beauty),寓意科学家在探索宇宙深奥规律的过程中,始终坚守对真理的执着追求与对至美的不懈探寻。该奖项覆盖数学、物理、工程三大领域,每个领域设置3项奖章,分别以埃米·诺特、陈省身、安德鲁·怀尔斯(数学领域),玛丽·居里、丁肇中、大卫·格罗斯(物理领域),吴健雄、朱棣文、高锟(工程领域)等9位科学巨匠命名。值得关注的是,每个领域专门设立了一项以著名女性科学家命名的奖项,今年共有克莱尔·瓦赞、刘若微、鲍哲南、庄小威4位女性科学家获奖,充分彰显了科学界对女性科研工作者的高度尊重,也展现了女性在基础科学领域的突出力量。

On the afternoon of May 18th, the press conference for the 2026 International Congress of Basic Science (ICBS 2026) was held at Tsinghua University, officially announcing the winners of the 2026 ICBS Medal and the Frontiers of Science Award. Nine top scientists from China and abroad were honored with the ICBS Medal. Among them, Claire Voisin, Horng-Tzer Yau, and Shou-Wu Zhang received the ICBS Medal in Mathematics; Andrea J. Liu, Yifang Wang, and Xiao-Gang Wen were awarded the ICBS Medal in Physics; and Zhenan Bao, Xiaowei Zhuang, and Feng Zhang were honored with the ICBS Medal in Engineering.

As a prestigious award established for the first time in 2026, the ICBS Medal aims to recognize scientists worldwide who have achieved revolutionary and groundbreaking results in basic science, celebrating their outstanding contributions to scientific progress. The obverse side of the medal features the portraits of scientific luminaries, while the reverse is inscribed with "For Truth and Beauty," symbolizing scientists' unwavering pursuit of truth and beauty in their exploration of the universe's profound laws. The award spans three major fields—Mathematics, Physics, and Engineering—with three medals in each category, named after nine scientific giants: Emmy Noether, Shiing-Shen Chern, and Andrew Wiles (Mathematics); Marie Curie, Samuel C.C. Ting, and David Gross (Physics); Chien-Shiung Wu, Steven Chu, and Charles K. Kao (Engineering). Notably, each field includes an award named after a renowned female scientist. This year, four female scientists—Claire Voisin, Andrea J. Liu, Zhenan Bao, and Xiaowei Zhuang—were honored, highlighting the scientific community's deep respect for women researchers and showcasing the remarkable contributions of women in basic science.



 

 

2026年ICBS数学领域基础科学奖章

ICBS Medal in Mathematics

 


“2026年ICBS埃米·诺特数学奖章授予克莱尔·瓦赞,以表彰其在霍奇理论与代数几何方面的开创性贡献,包括证否小平邦彦猜想、攻克格林(Green)猜想,以及建立起一系列具有变革意义的研究方法,极大地深化了人们对复簇、代数闭链(cycles)及其有理性性质的认知。”

克莱尔·瓦赞是一位杰出的数学家,她的研究从根本上推动了现代代数几何与霍奇理论的发展。她最重要的学术贡献包括:证否高维凯勒流形上的小平邦彦猜想,构建霍奇猜想的关键反例,以及成功证明一般曲线的格林猜想,成为现代代数几何领域的一项里程碑式成果。

瓦赞在代数几何的诸多分支方向上做出了许多奠基性的工作。她开创了对角线分解的相关研究,并在此框架下引入了特殊化方法,为法诺流形有理性问题的研究提供了强有力的工具。目前,她继续专注于代数闭链几何与算术的研究,这是代数几何的核心研究课题。

The ICBS Emmy Noether Medal in Mathematics for 2026 is awarded to Claire Voisin in recognition of her groundbreaking contributions to Hodge theory and algebraic geometry, including disproving the Kodaira conjecture, resolving the Green conjecture, and establishing a series of transformative research methods that have profoundly deepened our understanding of complex varieties, algebraic cycles, and their rationality properties.

Claire Voisin is an outstanding mathematician whose research has fundamentally advanced the development of modern algebraic geometry and Hodge theory. Her most significant academic contributions include disproving the Kodaira conjecture for high-dimensional Kähler manifolds, constructing key counterexamples to the Hodge conjecture, and successfully proving the Green conjecture for general curves, which stands as a landmark achievement in modern algebraic geometry.

Voisin has laid the foundation for numerous branches of algebraic geometry. She pioneered research on diagonal decomposition and introduced specialization methods within this framework, providing powerful tools for studying the rationality of Fano manifolds. Currently, she continues to focus on the geometry and arithmetic of algebraic cycles, a central research topic in algebraic geometry.

 

 

 

“2026年ICBS陈省身数学奖章授予姚鸿泽,以表彰其在数学物理学与随机矩阵理论方面的开创性贡献,包括发展局部松弛流方法及解决维格纳-戴森普适性猜想,建立了一套具有变革意义的工具集,深刻改变了人们对于量子动力学与安德森局域化的理解。”

姚鸿泽是一位杰出的数学物理学家,其学术工作从根本上重构了当代概率论与量子多体动力学的研究。他最重要的贡献包括:与合作者共同提出了局部松弛流方法,该方法通过对维格纳矩阵普适性的证明,推动了随机矩阵理论研究范式的转变。此后,他在量子唯一遍历性领域展开了一系列开创性工作,筑牢了人们理解无序量子系统的理论基石。

在随机带状矩阵谱分析的发展进程中,姚鸿泽还作出了多项关键性贡献。他改造了热流技术并将其应用于特征向量分析,扩展了分析研究体系,厘清了局域化与退局域化之间的转变机制。他持续融合物理直觉与复杂的分析手段,构建了核心理论框架,重新校准了在跨多学科背景下,对于复杂随机系统的理解。

In 2026, the ICBS Chern Medal in Mathematics was awarded to Horng-Tzer Yau in recognition of his groundbreaking contributions to mathematical physics and random matrix theory. These include developing the method of local relaxation flow and resolving the Wigner-Dyson universality conjecture, establishing a transformative set of tools that profoundly reshaped our understanding of quantum dynamics and Anderson localization.

Horng-Tzer Yau is an eminent mathematical physicist whose scholarly work has fundamentally redefined contemporary research in probability theory and quantum many-body dynamics. His most significant contributions include co-developing the local relaxation flow method, which, through its proof of Wigner matrix universality, catalyzed a paradigm shift in random matrix theory. Subsequently, he pioneered a series of groundbreaking works in quantum unique ergodicity, solidifying the theoretical foundation for understanding disordered quantum systems.

In the advancement of spectral analysis for random band matrices, Yau also made multiple pivotal contributions. He refined the heat flow technique and applied it to eigenvector analysis, expanding the analytical framework and clarifying the transition mechanisms between localization and delocalization. By consistently integrating physical intuition with sophisticated analytical methods, he constructed core theoretical frameworks that recalibrated interdisciplinary understanding of complex random systems.



 

 


“2026年ICBS安德鲁·怀尔斯数学奖章授予张寿武,表彰其对算术几何的变革性贡献,包括证明博戈莫洛夫猜想及推广格罗斯–查吉尔公式,构建阿拉克洛夫理论与自守形式的宏大理论体系,从而重塑了数论的版图。”

张寿武是一位杰出的数学家,其学术工作从根本上重塑了现代算术几何与数论领域的研究。他最重要的贡献包括:关于小点等分布定理的开创性工作,以及对数域上博戈莫洛夫猜想的严格证明。此后,他将格罗斯–查吉尔公式推广至全实域上的志村曲线,奠定了现代阿拉克洛夫理论的基石。

张寿武还为库达拉纲领与甘–格罗斯–普拉沙德猜想的发展,作出了诸多关键性的贡献。他开创了一种将动力系统与自守形式相统一的极具变革性的研究方法,为算术闭链的研究提供了深刻而简洁的洞见。他不断尝试将自然的几何现象与精密的分析工具相融合,为人们理解当代算术几何以及数学多学科交叉领域的问题,提供了重要的理论框架。

In 2026, the ICBS Andrew Wiles Medal was awarded to Shou-Wu Zhang in recognition of his transformative contributions to arithmetic geometry, including the proof of the Bogomolov conjecture and the generalization of the Gross-Zagier formula, as well as his construction of a grand theoretical framework encompassing Arakelov theory and automorphic forms—thereby reshaping the landscape of number theory.

Shou-Wu Zhang is a distinguished mathematician whose academic work has fundamentally reshaped modern research in arithmetic geometry and number theory. His most significant contributions include groundbreaking work on the equidistribution theorem for small points and the rigorous proof of the Bogomolov conjecture over number fields. Subsequently, he extended the Gross-Zagier formula to Shimura curves over totally real fields, laying the cornerstone for modern Arakelov theory.

Zhang has also made numerous pivotal contributions to the development of the Kudla program and the Gan-Gross-Prasad conjecture. He pioneered a revolutionary research methodology that unifies dynamical systems with automorphic forms, providing profound and elegant insights into the study of arithmetic cycles. By continuously integrating natural geometric phenomena with precise analytical tools, he has established crucial theoretical frameworks for understanding contemporary arithmetic geometry and interdisciplinary challenges in mathematics.



 


 

2026年ICBS物理领域基础科学奖章

ICBS Medal in Physics

 

 

 

“2026年ICBS玛丽·居里物理奖章授予刘若微,表彰其在堵塞(jamming)范式方面的开创性贡献,明确将堵塞相变界定为刚性的普适临界点,并将软度(softness)参数的机器学习方法融入理论体系,彻底改变了人们对无序固体与玻璃形成液体的理解。”

刘若微是一位杰出的理论物理学家,其学术成果深刻影响了当代软物质与统计物理两大研究领域。她最具影响力的学术贡献包括:提出了“堵塞相图(jamming phase diagram)”,将泡沫、玻璃及颗粒介质的研究统一于同一理论框架之下,推动了学科研究范式的重大变革。此后,她又展开了对堵塞相变(jamming transition)的前沿研究,为人们理解非晶材料如何转变为刚性状态奠定了核心理论基石。

刘若微还拓展了分析理论的应用范畴,通过引入基于机器学习的软度(softness)参数,阐释了玻璃形成液体与无序固体的特性,深化了对这类物质的认知。她将生物现象与精密的物理工程技术相结合,为可调物质(tunable matter)中协同功能(collective function)的涌现提供跨学科的研究范式。

The ICBS Marie Curie Medal in Physics for 2026 is awarded to Liu Ruowei in recognition of her groundbreaking contributions to the jamming paradigm. She definitively established jamming transitions as a universal critical point of rigidity and integrated machine learning approaches to the softness parameter into theoretical frameworks, revolutionizing our understanding of disordered solids and glass-forming liquids.

Liu Ruowei is an eminent theoretical physicist whose academic achievements have profoundly influenced two major research fields: soft matter and statistical physics. Her most impactful contributions include proposing the "jamming phase diagram," which unified the study of foams, glasses, and granular media under a single theoretical framework, driving a paradigm shift in the discipline. Subsequently, she pioneered cutting-edge research on jamming transitions, laying the foundational theoretical groundwork for understanding how amorphous materials acquire rigidity.

Liu further expanded the applications of analytical theory by introducing machine learning-based softness parameters to characterize glass-forming liquids and disordered solids, deepening our comprehension of these materials. By bridging biological phenomena with precision physical engineering, she established an interdisciplinary research paradigm for studying emergent collective functions in tunable matter.



 

 

 

“2026年ICBS丁肇中物理奖章授予王贻芳,表彰其率先发现了一种全新的中微子振荡模式并首次精确测量了混合角 Θ_13,他领导完成江门中微子实验 (JUNO)建设, 正以测量中微子质量顺序为目标,持续探索超越标准模型的新物理。”

王贻芳是一位杰出的物理学家,其学术成就深刻重塑了当代高能物理和中微子物理领域的研究。 他最具里程碑意义的贡献是通过大亚湾实验共同发现了中微子混合角 Θ_13,这一成果颠覆了学界对中微子振荡模式的固有认知,推动该领域研究迈入了全新的范式。此后,他牵头主持江门中微子实验项目,为全球攻克中微子质量顺序测量难题筑牢了基石。

在大型探测器技术发展与国际科研合作方面,王贻芳亦建树卓著。他通过设计超灵敏液体闪烁体系统,大幅提升反应堆反中微子的探测精度与甄别水平,拓宽了实验物理的研究边界。他长期深耕前沿领域,将深厚的物理理论洞察力与复杂的工程技术融合,搭建起关键理论框架,为重新理解跨学科视角下的当代粒子物理学奠定了重要基础。

In 2026, the ICBS Samuel C.C. Ting Medal in Physics was awarded to Yifang Wang in recognition of his pioneering discovery of a new neutrino oscillation mode and the first precise measurement of the mixing angle Θ_13. He led the completion of the Jiangmen Underground Neutrino Observatory (JUNO) and continues to explore new physics beyond the Standard Model with the goal of determining the neutrino mass ordering.

Yifang Wang is an outstanding physicist whose academic achievements have profoundly reshaped contemporary research in high-energy physics and neutrino physics. His most landmark contribution was the co-discovery of the neutrino mixing angle Θ_13 through the Daya Bay experiment, which overturned the scientific community's conventional understanding of neutrino oscillation patterns and propelled the field into a new paradigm. Subsequently, he spearheaded the JUNO project, laying a crucial foundation for global efforts to tackle the challenge of measuring the neutrino mass ordering.

Wang has also made remarkable contributions to the development of large-scale detector technology and international scientific collaboration. By designing ultra-sensitive liquid scintillator systems, he significantly enhanced the precision and discrimination capabilities of reactor antineutrino detection, expanding the frontiers of experimental physics. With long-term dedication to cutting-edge research, he combines profound theoretical insights with sophisticated engineering expertise, establishing key theoretical frameworks that provide an essential foundation for reinterpreting contemporary particle physics from an interdisciplinary perspective.



 

 

 

“2026年ICBS戴维·格罗斯物理奖章授予文小刚,表彰其在拓扑序与长程纠缠理论的开创性工作,他将这两大理论确立为理解量子物态与广义对称的基本组织原理,并在凝聚态物理、粒子物理、量子信息科学与范畴论之间,搭建起深刻的学科关联。”

文小刚是享誉国际的杰出物理学家,其学术工作重塑了现代凝聚态物理的理论体系。他最具影响力的贡献,包括提出拓扑序概念,并明确了长程纠缠为拓扑序的微观起源。这些成果突破了朗道(Landau)关于物质相的对称破缺理论,也超越了基于群论的对称认知,建立起凝聚态物理研究的全新范式。他提出弦网凝聚理论,构建了深刻的理论体系,阐明了规范相互作用与费米统计如何从局部量子比特中涌现,并可通过局部量子比特实现统一。

文小刚推动了将融合范畴与高阶范畴理论引入凝聚态物理领域的研究,确立了该理论体系(而非群论)作为描述拓扑量子物态、多体纠缠以及对称全息理论的核心数学框架。他持续深耕前沿研究,将凝聚态物理现象与精密的量子信息理论、数学范畴论深度融合,构建起关键理论框架,重新校准了人们对拓扑量子相、多体纠缠以及对称全息本质的认知,研究成果跨越多个学科领域。

In 2026, the ICBS David Gross Medal in Physics was awarded to Wen Xiao-Gang in recognition of his groundbreaking work on topological order and long-range entanglement theory. He established these two theories as fundamental organizing principles for understanding quantum states of matter and generalized symmetries, forging profound interdisciplinary connections between condensed matter physics, particle physics, quantum information science, and category theory.

Wen Xiao-Gang is an internationally renowned physicist whose academic work has reshaped the theoretical framework of modern condensed matter physics. His most influential contributions include proposing the concept of topological order and identifying long-range entanglement as its microscopic origin. These achievements broke through Landau's symmetry-breaking theory of phases of matter and transcended group-theory-based symmetry understanding, establishing a new paradigm for condensed matter physics research. He introduced the string-net condensation theory, constructing a profound theoretical system that elucidates how gauge interactions and Fermi statistics emerge from local qubits and can be unified through them.

Wen Xiao-Gang pioneered the introduction of fusion categories and higher category theory into condensed matter physics, establishing this theoretical framework (rather than group theory) as the core mathematical foundation for describing topological quantum states, many-body entanglement, and symmetry holography. Continuously advancing cutting-edge research, he deeply integrated condensed matter phenomena with sophisticated quantum information theory and mathematical category theory, constructing key theoretical frameworks that recalibrated our understanding of topological quantum phases, many-body entanglement, and the essence of symmetry holography. His research spans multiple disciplines.



 

 

2026年ICBS工程领域基础科学奖章

ICBS Medal in Engineering

 

 

“2026年ICBS吴健雄工程奖章授予鲍哲南,以表彰其在类皮肤电子材料领域的开创性贡献。她发明了可拉伸、自修复电子材料,突破刚性硅基材料的局限,为电子皮肤、柔性生物电子和以人为本的电子技术奠定了基础。”

鲍哲南是国际顶尖材料科学家,其开创性的研究深刻塑造了有机电子学、柔性生物电子学和以人为本的电子技术领域。她最具影响力的研究成果包括:研发高性能有机半导体、首个全印刷塑料晶体管以及高速可拉伸聚合物集成电路——这些突破打破了刚性、易碎硅基材料对电子技术的限制。上述科研进展为"电子皮肤"的材料研发与制备工艺奠定了核心基础,验证了合成材料可将生物组织的柔软性、可拉伸性、自修复能力和耐久性,与精密的电子功能结合。

鲍哲南在聚合物电子材料领域的基础性研究,为能够与人体紧密适配的可穿戴、可植入式系统的发展筑牢了根基,广泛应用于健康医疗、智能机器人、假肢设备以及人机交互等领域。秉持同样的科研理念,她研发出神经弦(NeuroString)——一种细如发丝的电子传感纤维,运用于神经工程技术领域,制备微创植入式器件,同时应用于心脏、胃肠道、泌尿系统以及长期生理体征的精准监测等。她持续深耕前沿研究,将化学工程与先进电子技术深度融合,提出一系列基础性材料设计理念与制备方法,在合成材料、电子技术与生命体系交叉融合的全新研究领域。

In 2026, the ICBS Wu Chien-Shiung Engineering Medal was awarded to Zhenan Bao in recognition of her pioneering contributions to the field of skin-like electronic materials. She invented stretchable, self-healing electronic materials, breaking through the limitations of rigid silicon-based materials and laying the foundation for electronic skin, flexible bioelectronics, and human-centered electronic technologies.

Zhenan Bao is a world-leading materials scientist whose groundbreaking research has profoundly shaped the fields of organic electronics, flexible bioelectronics, and human-centered electronic technologies. Her most influential achievements include the development of high-performance organic semiconductors, the first fully printed plastic transistors, and high-speed stretchable polymer integrated circuits—these breakthroughs have overcome the constraints of rigid and brittle silicon-based materials on electronic technology. These advancements established the core foundation for the material development and fabrication processes of "electronic skin," demonstrating that synthetic materials can combine the softness, stretchability, self-healing capability, and durability of biological tissues with sophisticated electronic functionality.

Bao's fundamental research in polymer electronic materials has laid the groundwork for the development of wearable and implantable systems that can closely integrate with the human body, with broad applications in healthcare, smart robotics, prosthetic devices, and human-machine interaction. Guided by the same research philosophy, she developed NeuroString—a hair-thin electronic sensing fiber used in neuroengineering to create minimally invasive implantable devices, as well as for precise monitoring of cardiac, gastrointestinal, urinary, and long-term physiological signals. She continues to push the boundaries of cutting-edge research, deeply integrating chemical engineering with advanced electronics to propose a series of fundamental material design concepts and fabrication methods in the emerging interdisciplinary field of synthetic materials, electronic technologies, and biological systems.



 

 

 

“2026年ICBS朱棣文工程奖章授予庄小威,表彰其发明了STORM超分辨显微镜与MERFISH空间分辨转录组学,突破了光学衍射极限,深刻改变了人类对生命纳米尺度结构与空间结构的认知。”

庄小威是国际顶尖生物物理学家,其工作深刻塑造了现代生物成像与空间基因组学的发展格局。她最具影响力的成果是发明了随机光学重建显微镜(STORM)这一超分辨成像技术,成功突破了光学衍射极限。这一重大突破为解析细胞纳米尺度结构提供了关键支撑,揭示了细胞内分子组分的排布规律,其精度达到了此前学界认为无法实现的水平。

在高分辨率生物分析领域,庄小威还作出了多项关键贡献。她率先研发出空间分辨转录组学技术MERFISH(多重抗错荧光原位杂交技术),能够在单个细胞内同时定位数千种不同RNA分子。该技术搭建起分子生物学与空间背景相融合的研究框架,为解析组织功能结构提供了重要思路。她始终致力于将物理原理与先进成像技术相结合,研发出一系列基础性工具,重塑了人们在多学科视角下,对于细胞组织与基因表达的认知。

In 2026, the ICBS Steven Chu Medal in Engineering was awarded to Xiaowei Zhuang in recognition of her invention of STORM super-resolution microscopy and MERFISH spatially resolved transcriptomics, which broke the optical diffraction limit and profoundly transformed humanity's understanding of nanoscale and spatial structures in life.

Xiaowei Zhuang is a world-leading biophysicist whose work has profoundly shaped the development of modern biological imaging and spatial genomics. Her most influential achievement is the invention of stochastic optical reconstruction microscopy (STORM), a super-resolution imaging technique that successfully surpassed the optical diffraction limit. This groundbreaking advancement provided critical support for analyzing cellular structures at the nanoscale, revealing the organizational principles of molecular components within cells with a precision previously deemed unattainable by the scientific community.

In the field of high-resolution biological analysis, Zhuang has also made multiple key contributions. She pioneered the development of MERFISH (multiplexed error-robust fluorescence in situ hybridization), a spatially resolved transcriptomics technology capable of simultaneously localizing thousands of different RNA molecules within a single cell. This technique established a research framework that integrates molecular biology with spatial context, offering crucial insights into tissue functional architecture. She has consistently dedicated herself to combining physical principles with advanced imaging technologies, developing a series of foundational tools that have reshaped multidisciplinary perspectives on cellular organization and gene expression.



 

 

 

“2026年ICBS高锟工程奖章授予张锋,以表彰其在光遗传学领域的开创性研究,率先将 CRISPR-Cas9技术应用于哺乳动物基因组编辑,构建起一套具有变革性的研究工具体系,深刻变革了生物医学研究、分子诊断技术,拓宽了基因治疗的发展前景。”

张锋是国际杰出分子生物学家与生物工程学家,其学术成就从根本上塑造了当代神经科学与基因组结构的相关研究。他最具标志性的贡献包括:联合开创了光遗传学技术,该技术通过实现对脑细胞的光驱动调控,彻底改变了神经网络研究的范式。此后,他率先证实CRISPR-Cas9技术可用于真核生物基因组编辑,为现代生物技术奠定了核心基石。

在可编程生物分子技术的发展过程中,张锋还作出了多项关键贡献。他通过优化 Cas12 与 Cas13酶,将其应用于多维度DNA/RNA 操控,拓展了“核酸酶应用范围”,并与合作者共同开发了夏洛克(SHERLOCK)——一种超高灵敏的诊断技术,显著提升了分子检测的精准度与解析能力。他潜心钻研前沿领域,长期致力于融合自然生物现象与前沿工程技术,构建起关键理论框架,重新界定了人们对细胞动态机制的认知,为跨学科领域的基因治疗开拓了全新的发展方向。

In 2026, the ICBS Charles K. Kao Medal in Engineering was awarded to Feng Zhang in recognition of his groundbreaking research in optogenetics. He pioneered the application of CRISPR-Cas9 technology in mammalian genome editing, establishing a transformative toolkit that has profoundly reshaped biomedical research and molecular diagnostics while expanding the horizons of gene therapy.

Feng Zhang is a world-renowned molecular biologist and bioengineer whose academic achievements have fundamentally shaped contemporary neuroscience and genomic research. His most iconic contributions include co-developing optogenetics—a technology that revolutionized neural circuit studies by enabling light-controlled manipulation of brain cells. Subsequently, he became the first to demonstrate CRISPR-Cas9’s utility in eukaryotic genome editing, laying a cornerstone for modern biotechnology.

Throughout the evolution of programmable biomolecular technologies, Zhang has made multiple pivotal advances. By optimizing Cas12 and Cas13 enzymes for multidimensional DNA/RNA manipulation, he broadened the "nuclease application spectrum" and co-developed SHERLOCK, an ultra-sensitive diagnostic platform that significantly enhanced the precision and resolution of molecular detection. Dedicated to cutting-edge exploration, he has long focused on integrating natural biological phenomena with advanced engineering to construct critical theoretical frameworks. His work has redefined our understanding of cellular dynamics and opened new frontiers for interdisciplinary gene therapy.




*This article is reprinted from the SIMIS